Resultats - Síntesis Orgànica Estereoselectiva
Síntesis Orgànica Estereoselectiva
| Tesis Doctorals Dirigides / Theses |
| 2021 | 2022 | 2023 | 2024 | 2025 |
|---|
| Títol: Insights into Aminofluorination Strategies and Sphingosine Analogue Synthesis towards the Development of Selective SphK2 Inhibitors |
| Autor: Granell Fort, Albert |
| Director: Matheu Malpartida, María Isabel; Díaz Giménez, María Yolanda |
| Universitat: N/D |
| Any: 2024 |
| País: N/D |
| Títol: Targeting Des1: Syntheses of ceramide analogues with a rigid scaffold, inhibitory assays, and AF2-assisted structural insights reveal PR280 as a potent inhibitor |
| Autor: Rivero Prieto, Pablo |
| Director: Díaz Giménez, María Yolanda; Matheu Malpartida, María Isabel |
| Universitat: N/D |
| Any: 2024 |
| País: N/D |
| Títol: Reagents and methodologies for the introduction of thiofluoroalkyl and fluorosulfur motifs |
| Autor: Bernús Pérez, Miguel |
| Director: Boutureira Martín, Omar |
| Universitat: N/D |
| Any: 2023 |
| País: N/D |
| Títol: Stereoselective synthesis of fluorinated glycoconjugates.Tuning physicochemical parameters for therapeutic drug development |
| Autor: Bascuas Jiménez De Bagües, Isabel |
| Director: Boutureira Martín, Omar |
| Universitat: N/D |
| Any: 2022 |
| País: N/D |
| Publicacions en Revista / Papers |
| 2021 | 2022 | 2023 | 2024 | 2025 |
|---|
| Títol: Impact of Fluorine Pattern on Lipophilicity and Acid-Base Properties of 2-(Thiofluoroalkyl)pyridines: Insights from Experiments and Statistical Modeling |
| Autors: Bernus, Miguel; Nunez, Gonzalo D; Hartley, Will C; Guasch, Marc; Mestre, Jordi; Besora, Maria; Carbo, Jorge J; Boutureira, Omar |
| Any: 2025 Clau: Article |
| Revista: Journal Of Medicinal Chemistry |
| País: N/D |
| Títol: Syntheses of differentially fluorinated triazole-based 1-deoxysphingosine analogues en route to SphK inhibitors |
| Autors: Cardona, Adria; Ivanova, Varbina; Beltran-Debon, Raul; Barril, Xavier; Castillon, Sergio; Diaz, Yolanda; Matheu, M Isabel |
| Any: 2025 Clau: Article |
| Revista: Organic & Biomolecular Chemistry |
| País: N/D |
| Títol: Electrophilic glycoluril-based reagents for atom-economic thiocyanation and selenocyanation of (hetero)arenes |
| Autors: Casasus, Paula; Mestre, Jordi; Radlowska, Roksana; Bernus, Miguel; Boutureira, Omar |
| Any: 2025 Clau: Article |
| Revista: Organic & Biomolecular Chemistry |
| País: N/D |
| Títol: A modular flow platform for sulfur(VI) fluoride exchange ligation of small molecules, peptides and proteins |
| Autors: Bernus, Miguel; Mazzarella, Daniele; Stanic, Jelena; Zhai, Ziran; Yeste-Vazquez, Alejandro; Boutureira, Omar; Gargano, Andrea F G; Grossmann, Tom N; Noel, Timothy |
| Any: 2024 Clau: Article |
| Revista: Nature Synthesis |
| País: N/D |
| Títol: In-Flow Generation of Thionyl Fluoride (SOF2) Enables the Rapid and Efficient Synthesis of Acyl Fluorides from Carboxylic Acids |
| Autors: Mazzarella, Daniele; Stanic, Jelena; Bernus, Miguel; Mehdi, Arad Seyed; Henderson, Cassandra J; Boutureira, Omar; Noel, Timothy |
| Any: 2024 Clau: Article |
| Revista: Jacs Au |
| País: N/D |
| Títol: Targeting dihydroceramide desaturase 1 (Des1): Syntheses of ceramide analogues with a rigid scaffold, inhibitory assays, and AlphaFold2-assisted structural insights reveal cyclopropenone PR280 as a potent inhibitor |
| Autors: Rivero, Pablo; Ivanova, Varbina; Barril, Xavier; Casampere, Mireia; Casas, Josefina; Fabrias, Gemma; Diaz, Yolanda; Matheu, M Isabel |
| Any: 2024 Clau: Article |
| Revista: Bioorganic Chemistry |
| País: N/D |
| Títol: Tetrafluoroethylation of Electron-Rich Alkenyl Iodides Enabled by in situ Generation of Solvent-Stabilized "Ligandless" CuCF2CF2H |
| Autors: Segovia, Cristina M; Porto, Luana L T N; Casasus, Paula; Bascuas, Isabel; Ahmad, Amena; Mestre, Jordi; Bernus, Miguel; Castillon, Sergio; Baker, R Tom; Boutureira, Omar |
| Any: 2024 Clau: Article |
| Revista: Advanced Synthesis & Catalysis |
| País: N/D |
| Títol: A unified flow strategy for the preparation and use of trifluoromethyl-heteroatom anions |
| Autors: Spennacchio, Mauro; Bernus, Miguel; Stanic, Jelena; Mazzarella, Daniele; Colella, Marco; Douglas, James J; Boutureira, Omar; Noel, Timothy |
| Any: 2024 Clau: Article |
| Revista: Science |
| País: N/D |
| Títol: Bench-Stable Electrophilic Reagents for the Direct Di- and Trifluoroethylthiolation of Indoles |
| Autors: Casasus, Paula; Mestre, Jordi; Bernus, Miguel; Castillon, Sergio; Boutureira, Omar |
| Any: 2023 Clau: Article |
| Revista: Advanced Synthesis & Catalysis |
| País: N/D |
| Títol: Bringing Selectivity in H/D Exchange Reactions Catalyzed by Metal Nanoparticles through Modulation of the Metal and the Ligand Shell |
| Autors: Martinez-Espinar, Francisco; Salom-Catala, Antoni; Breso-Femenia, Emma; Claver, Carmen; Baletto, Francesca; Ricart, Josep M; Chaudret, Bruno; Carbo, Jorge J; Godard, Cyril; Castillon, Sergio |
| Any: 2023 Clau: Article |
| Revista: Inorganic Chemistry |
| País: N/D |
| Títol: Stereoselective access to 2-deoxy-2-trifluoromethyl sugar mimetics by trifluoromethyl-directed 1,2-trans glycosylation |
| Autors: Mestre, Jordi; Bascuas, Isabel; Bernus, Miguel; Castillon, Sergio; Boutureira, Omar |
| Any: 2023 Clau: Article |
| Revista: Organic Chemistry Frontiers |
| País: N/D |
| Títol: Probing Site-Selective Conjugation Chemistries for the Construction of Homogeneous Synthetic Glycodendriproteins |
| Autors: Cobo, Isidro; Matheu, M Isabel; Castillon, Sergio; Davis, Benjamin G; Boutureira, Omar |
| Any: 2022 Clau: Article |
| Revista: Chembiochem |
| País: N/D |
| Títol: Revealing 2-dimethylhydrazino-2-alkyl alkynyl sphingosine derivatives as sphingosine kinase 2 inhibitors: Some hints on the structural basis for selective inhibition |
| Autors: Corro-Moron, Macarena; Granell, Albert; Ivanova, Varbina; Domingo, Elena; Beltran-Debon, Raul; Barril, Xavier; Sanz, Maria-Jesus; Matheu, M Isabel; Castillon, Sergio; Diaz, Yolanda |
| Any: 2022 Clau: Article |
| Revista: Bioorganic Chemistry |
| País: N/D |
| Títol: Association between histological diaphragm atrophy and ultrasound diaphragm expiratory thickness in ventilated patients |
| Autors: Dot, Irene; Perez-Teran, Purificacion; Frances, Albert; Diaz, Yolanda; Vila-Vilardell, Clara; Salazar-Degracia, Anna; Chalela, Roberto; Barreiro, Esther; Rodriguez-Fuster, Alberto; Ramon Masclans, Joan; Marin-Corral, Judith |
| Any: 2022 Clau: Article |
| Revista: Journal Of Intensive Care |
| País: N/D |
| Títol: Electrophilic Reagents for the Direct Incorporation of Uncommon SCF2CF2H and SCF2CF3 Motifs |
| Autors: Mestre, Jordi; Bernu, Miguel; Castillon, Sergio; Boutureira, Omar |
| Any: 2022 Clau: Article |
| Revista: Journal Of Organic Chemistry |
| País: N/D |
| Títol: New Co and Mn Catalysts Bearing ONO Ligands Containing Nucleophile for the Coupling of CO2 and Propylene Oxide |
| Autors: Viciano, Monica; Munoz, Bianca K; Zangrando, Ennio; Godard, Cyril; Castillon, Sergio; Blanco Gonzalez, Ma Dolores; Garcia-Ruiz, Monica; Claver, Carmen |
| Any: 2022 Clau: Article |
| Revista: Catalysts |
| País: N/D |
| Títol: Toward the stereoselective synthesis of zaragozic acid framework: A desilylation-aldol reaction approach |
| Autors: Kurniawan YD; Tuck KL; Castillón S; Robinson AJ |
| Any: 2021 Clau: Article |
| Revista: Tetrahedron Letters |
| País: N/D |
| Títol: Metal complexes bearing ONO ligands as highly active catalysts in carbon dioxide and epoxide coupling reactions |
| Autors: Munoz, Bianca K; Viciano, Monica; Godard, Cyril; Castillon, Sergio; Garcia-Ruiz, Monica; Gonzalez, Ma Dolores Blanco; Claver, Carmen |
| Any: 2021 Clau: Article |
| Revista: Inorganica Chimica Acta |
| País: N/D |
| Llibres / Books |
| 2021 | 2022 | 2023 | 2024 | 2025 |
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| Capítols de Llibre / Book chapters |
| 2021 | 2022 | 2023 | 2024 | 2025 |
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| Altres Documents / Other documents |
| 2021 | 2022 | 2023 | 2024 | 2025 |
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| Patents Sol.licitades / Patents |
| 2021 | 2022 | 2023 | 2024 | 2025 |
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| Congressos / Conferences |
| 2021 | 2022 | 2023 | 2024 | 2025 |
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